Organs-on-Chip Designer

Organs-on-Chips (OoCs) are testing platforms for the pharmaceutical, cosmetic, and chemical industries. They are composed of miniaturized organ tissues (so-called organ modules) that are connected via a microfluidic channel network and, by this, emulate human or other animal physiology on a miniaturized chip.

The design of those chips, however, requires a sophisticated orchestration of numerous aspects, such as the size of organ modules, the required shear stress on membranes, the dimensions and geometry of channels, pump pressures, etc. These are used to define an initial design. This can then be translated to a 2D network as well as extruded and exported as a 3D geometry of the microfluidic channel network for subsequent simulations or the desired device, including the chip specifications for fabrication.

In our paper “Design Automation for Organs-on-Chip”, we are proposing a method for the inital design of Organs-on-Chip.

If you use the implementation for your research, we would be thankful if you referred to it by citing the following publication:

@article{fink2021improving,
   title={Design Automation for Organs-on-Chip},
   author={Emmerich, Maria and Ebner, Philipp and Wille, Robert}},
   booktitle={Design, Automation and Test in Europe (DATE)},
   year={2024}
}

More on our work on microfluidics is summarized in this page.