↑ Microfluidics

Gradient Generator

This page provides the Gradient Generator: a tool allowing to automatically create designs for tree-shaped concentration gradient generators. Such devices are used to mix two fluids with different concentration values and provide various mixtures of these fluids (i.e., mixtures with certain concentration values) at corresponding outlets.

The concentration values at the outlets as well as the number of outlets can be specified by the user. Besides this, the user only has to specify basic input parameters, such as the channel width, fluid viscosity, flow rates etc. Based on this parameters a design of a tree-shaped concentration gradient generator is automatically generated and can then be downloaded as Scalable Vector Graphics (SVG) file.

Details of the approach are summarized in the paper entitled “Automatic Design of Microfluidic Gradient Generators”.

In case of questions/problems, please contact us through microfluidics.cda@xcit.tum.de.

More on our work on microfluidics is summarized in this page.

How to cite

If you use the tool for your research, we would be thankful if you referred to it by citing the following publication:

@article{fink2021gradientgeneration,
  title        = {Automatic Design of Microfluidic Gradient Generators},
  author       = {Fink, Gerold and Mitteramskogler, Tina and Hintermüller, Marcus and Jakoby, Bernhard and Wille, Robert},
  journal      = {IEEE Access},
  year         = {2022},
}

This work is part of the Munich Microfluidics Toolkit, described in the following paper :

@INPROCEEDINGS{iccad_2025_mmft,
  AUTHOR        = {R. Wille and P. Ebner and M. Emmerich and M. Takken},
  TITLE         = {{The Munich Microfluidics Toolkit: Design Automation and Simulation Tools for Microfluidic Devices}},
  BOOKTITLE     = {International Conference on Computer Aided Design (ICCAD)},
  YEAR          = {2025},
  ADDENDUM      = {A overview of the toolkit is available at \url{https://www.cda.cit.tum.de/research/microfluidics/mmft/}},
}